Hrt and menopausal flushes and sweats control: a combination of oestrogen and progestogen

HRT AND MENOPAUSAL FLUSHES AND SWEATS CONTROL: A COMBINATION OF OESTROGEN AND PROGESTOGEN
A combination of oestrogen and progestogen may be recommended for dealing with hot flushes and night sweats if you still have your uterus. When the uterus has been removed, the use of oestrogen alone is considered a safe way to reduce the impact of flushes. High doses of progestogen alone are occasionally helpful in controlling them, but this approach is usually suggested only if oestrogen therapy is not recommended or tolerated.
Any doctor who prescribes HRT to help women with flushes will know that this symptom responds very well to oestrogen, often within a week. If you are a woman with debilitating or embarrassing flushes, the possibility of getting relief in such a short time may be persuasive. Some questions remain, however, about Jiow much of the benefit is due to HRT and how much to the psychological support the doctor provides.
Research shows that a significant number of women experience improvements in flush frequency and severity when they take a medication lacking any active ingredient. This is known as a placebo response - that is, the patient's symptoms are relieved when a harmless substance, like a sugar pill, is substituted for a biologically active agent. Too few studies of menopausal therapies, of both the prescribed and 'alternative' kind, have been sufficiently well designed to separate the effectiveness of the therapy from a woman's response to the empathy, support and interest shown by her practitioner. Of three major studies of oestrogen therapy for hot flushes that have taken the placebo response into account, all have demonstrated an improvement.
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